Press Release

Notice Concerning the Establishment of OrphanPacific, Inc.

It is announced that OrphanPacific Inc., a manufacturing and sales company of ethical drugs with a focus on orphan drugs (drugs for treating rare diseases), has been established on May 1, 2012, with funding from CMIC HOLDINGS Co., Ltd. (Representative Director: Kazuo Nakamura) and MEDIPAL HOLDINGS CORPORATION (Representative Director: Shuichi Watanabe).

1. Company Name: OrphanPacific, Inc.
2. Established: May 1, 2012
3. Location: Kongo Building 3F, 7-10-4 Nishigotanda, Shinagawa-ku, Tokyo
4. Management:
President Kunihide Ichikawa
(Managing Director, CMIC HOLDINGS Co., Ltd.)
Vice President Masanori kawahara
(Executive Officer, MEDIPAL HOLDINGS CORPORATION)
Director Masahiro Takasu
(Corporate Planning Division Deputy Director, CMIC HOLDINGS Co., Ltd.)
Director (part-time) Toshihide Yoda
(Managing Director, MEDIPAL HOLDINGS CORPORATION)
Director (part-time) Makoto Matsukawa
(Executive Officer, CMIC HOLDINGS Co., Ltd.)
5. Capital: 100 million yen
6. Shareholders: CMIC HOLDINGS Co., Ltd. 51%
MEDIPAL HOLDINGS CORPORATION 49%
7. Main Line of Business: Manufacturing and sales of pharmaceutical products
8. URL: http://www.orphanpacific.com/